A Rapid and Efficient Microwave-Assisted Synthesis of Substituted 3-Phenylpropionic Acids from Benzaldehydes in Minutes.

Sharma , A and Joshi, B P and Sinha, Arun K (2003) A Rapid and Efficient Microwave-Assisted Synthesis of Substituted 3-Phenylpropionic Acids from Benzaldehydes in Minutes. Chemistry Letters, 32 (12). pp. 1186-67. ISSN 0366-7022

Full text not available from this repository.

Official URL: http://www.csj.jp/journals/chem-lett/index.html

Abstract

A convenient, inexpensive, and efficient synthesis of 3-phenylpropionic acids (1a–1f) by reacting benzaldehyde (2a–2f) and malonic acid in acetic acid and piperidine into cinnamic acid (3a–3f) in 77 to 89% followed by its reduction with PdCl2 in the biphase of formic acid and aqueous sodium hydroxide is reported under microwave irradiation which utilizes short reaction time ranging 5 to 7 min to provide 1a–1f in moderate to high yield (69–86%) depending upon methoxy, methylenedioxy, and hydroxy groups present at the phenyl ring.

Item Type:	Article
Subjects:	Nanotechnology
Divisions:	UNSPECIFIED
Depositing User:	Dr. Aparna Maitra Pati
Date Deposited:	27 Dec 2011 07:31
Last Modified:	10 Feb 2012 07:50
URI:	http://ihbt.csircentral.net/id/eprint/720

Actions (login required)

View Item