Yadav, S C and Kumari, A and Yadav, R (2011) Development of peptide and protein nanotherapeutics by nanoencapsulation and nanobioconjugation. Peptides, 32 (1). pp. 173-187.

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Abstract

The targeted delivery of therapeutic peptide by nanocarriers systems requires the knowledge of interactions of nanomaterials with the biological environment, peptide release, and stability of therapeutic peptides. Therapeutic application of nanoencapsulated peptides are increasing exponentially and >1000 peptides in nanoencapsulated form are in different clinical/trial phase. This review covers current scenario of therapeutic protein and peptides encapsulation on polymer to metallic nanocarriers including methods of protein encapsulation, peptide bioconjugation on nanoparticles, stability enhancement of encapsulated proteins and its biomedical applications.

Item Type:	Article
Uncontrolled Keywords:	Peptide therapeutics; Peptide nanomedicines; Nanoencapsulation; Nanocarriers; Protein nanoparticles interaction; Bioconjugation
Subjects:	Nanotechnology
Divisions:	UNSPECIFIED
Depositing User:	Dr. Aparna Maitra Pati
Date Deposited:	30 Dec 2011 04:54
Last Modified:	30 Dec 2011 04:54
URI:	http://ihbt.csircentral.net/id/eprint/650

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