Kumar , Rakesh and Sharma , Prabha and Shard , Amit and Tewary, D K and Nadda , Gireesh and Sinha, Arun K (2012) Chalcones as promising pesticidal agents against diamondback moth (Plutella xylostella): microwave-assisted synthesis and structure–activity relationship. Medicinal Chemistry Research, 21. pp. 922-931.

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A series of chalcones (A–CH=CH–CO–B) were synthesized under microwave irradiation, and for the first time their pesticidal activity against diamondback moth (Plutella xylostella) was evaluated to identify the promising lead structures. The structure–activity relationship (SAR) analysis revealed that electron-withdrawing substituents on ring A of chalcone provided good pesticidal agents, whereas, ring B can bear either electron-withdrawing or electron-releasing substituents. Moreover, compound 22 having para-Cl substitution on ring A as well on ring B showed maximum activity with LC50 value of 170.24 lg mL-1.

Item Type: Article
Uncontrolled Keywords: Plutella xylostella; Chalcones; Pesticidal; Structure–activity relationship; Microwave
Subjects: Natural Product Chemistry
Pest and Pesticides
Depositing User: Dr. Aparna Maitra Pati
Date Deposited: 03 Jan 2013 10:48
Last Modified: 03 Jan 2013 10:48
URI: http://ihbt.csircentral.net/id/eprint/1204

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