Kumar, Vishal and Sharma, U and Kumar, P and Kumar, Neeraj and Singh , Bikram (2011) Silica-Supported Boric Acid with Ionic Liquid: A Novel Recyclable Catalytic System for One-Pot Three-Component Mannich Reaction. Journal of Chemistry.Pharm.Bull, 59 (5). pp. 639-645.

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A rapid and efficient silica-supported boric acid/ionic liquid ([bmim][PF6]), catalyzed, one-pot three-component Mannich reaction has been carried out to synthesize b -amino carbonyl compounds at room temperature. The reaction afforded desired products in excellent yields with moderate to good diastereoselectivity. The method provides a novel modification of three-component Mannich reaction in terms of mild reaction conditions, clean reaction profiles, low amount of catalyst, recyclability of catalyst and a simple workup procedure. The present report first time describes the preparation of H3BO3–SiO2 catalyst and its use with [bmim][PF6], to synthesize Mannich products. The catalyst can be reused at least seven times.

Item Type: Article
Uncontrolled Keywords: b -amino carbonyl compound; boric acid; ionic liquid; Mannich reaction; solid-supported catalyst
Subjects: Plant sciences
Natural Product Chemistry
Depositing User: Dr. Aparna Maitra Pati
Date Deposited: 08 Feb 2012 06:02
Last Modified: 13 Feb 2012 05:03
URI: http://ihbt.csircentral.net/id/eprint/944

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