Kumar, Vishal and Sharma, U and Kumar, P and Kumar, Neeraj and Singh , Bikram (2011) Silica-Supported Boric Acid with Ionic Liquid: A Novel Recyclable Catalytic System for One-Pot Three-Component Mannich Reaction. Journal of Chemistry.Pharm.Bull, 59 (5). pp. 639-645.
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Abstract
A rapid and efficient silica-supported boric acid/ionic liquid ([bmim][PF6]), catalyzed, one-pot three-component Mannich reaction has been carried out to synthesize b -amino carbonyl compounds at room temperature. The reaction afforded desired products in excellent yields with moderate to good diastereoselectivity. The method provides a novel modification of three-component Mannich reaction in terms of mild reaction conditions, clean reaction profiles, low amount of catalyst, recyclability of catalyst and a simple workup procedure. The present report first time describes the preparation of H3BO3–SiO2 catalyst and its use with [bmim][PF6], to synthesize Mannich products. The catalyst can be reused at least seven times.
Item Type: | Article |
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Uncontrolled Keywords: | b -amino carbonyl compound; boric acid; ionic liquid; Mannich reaction; solid-supported catalyst |
Subjects: | Plant sciences Natural Product Chemistry |
Divisions: | UNSPECIFIED |
Depositing User: | Dr. Aparna Maitra Pati |
Date Deposited: | 08 Feb 2012 06:02 |
Last Modified: | 13 Feb 2012 05:03 |
URI: | http://ihbt.csircentral.net/id/eprint/944 |
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