Sinha, Arun K and Joshi, B P and Sharma, A and Kumar, V and Acharya, Ruchi (2007) Microwave-Assisted Mild Conversion of Natural Dihydrotagetone into 5-Isobutyl-3-methyl-4,5-dihydro-2(3H)-furanone, an Analogue of Whisky Lactone*. Australian Journal of Chemistry, 60 (2). pp. 124-127.
Full text not available from this repository.Abstract
A microwave-assisted mild protocol is developed for the synthesis of 5-isobutyl-3-methyl-4,5-dihydro-2(3H)-furanone, an analogue of whisky lactone, from dihydrotagetone, an acyclic monoterpenoid obtained from Tagetes minuta. The methodology involved oxidation of dihydrotagetone in the presence of sodium metaperiodate/potassium permanganate/alumina to give 2,6-dimethyl-4-oxo-heptanoic acid, which upon reduction and subsequent lactonization provided 5-isobutyl-3-methyl-4,5-dihydro-2(3H)-furanone. The reaction is also conducted under conventional conditions and is compared with the microwave method.
Item Type: | Article |
---|---|
Subjects: | Natural Product Chemistry |
Divisions: | UNSPECIFIED |
Depositing User: | Dr. Aparna Maitra Pati |
Date Deposited: | 30 Dec 2011 05:01 |
Last Modified: | 03 Jan 2013 12:57 |
URI: | http://ihbt.csircentral.net/id/eprint/657 |
Actions (login required)
View Item |