Bhandari, P and Kumar, Neeraj and Singh , Bikram and Gupta, A P and Kaul, V K (2006) Micro-LC Determination of Swertiamarin in Swertia species and Bacoside-A in Bacopa monnieri. Chromatographia, 64 (9-10). pp. 599-602. ISSN 0009-5893

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A microanalytical HPLC technique has been developed for determination of swertiamarin in Swertia species and bacoside-A in Bacopa monnieri. Small quantities (‡2 mg) of powdered plant material are required for analysis. The limits of detection (LOD) of swertiamarin and bacoside-A are 500 pg and 4,000 ng, respectively, in 2 mg plant material. Dried plant material from S. cordata and S. chirata contained 5.59 and 0.44% swertiamarin, respectively, and B. monnieri contained 0.12% bacoside-A. The simplicity, accuracy, and reproducibility of the method enable its use for estimation of marker compounds.

Item Type: Article
Uncontrolled Keywords: Column liquid chromatography; Microanalytical technique; Marker compounds; Swertiamarin; Bacoside-A
Subjects: Natural Product Chemistry
Depositing User: Dr. Aparna Maitra Pati
Date Deposited: 27 Dec 2011 08:24
Last Modified: 06 Feb 2012 06:36

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