Shanmugam, V (2005) Role of extracytoplasmic leucine rich repeat proteins in plant defence mechanisms. Microbiological Research, 160. pp. 83-94.

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Plant–pathogen interactions involve highly complex series of reactions in disease development. Plants are endowed with both, resistance and defence genes. The activation of defence genes after contact with avirulence gene products of pathogens depends on signals transduced by leucine-rich repeats (LRRs) contained in resistance genes. Additionally, LRRs play roles for various actions following ligand recognition. Polygalacturonase inhibiting proteins (PGIPs), the only plant LRR protein with known ligands, are pectinase inhibitors, bound by ionic interactions to the extracellular matrix (ECM) of plant cells. They have a high affinity for fungal endopolygalacturonases (endoPGs). PGIP genes are organised in families encoding proteins with similar physical characteristics but different specificities. They are induced by infection and stress related signals. The molecular basis of PG–PGIP interaction serves as a model to understand the evolution of plant LRR proteins in recognising non-self-molecules. Extensins form a different class of structural proteins with repetitive sequences. They are also regulated by wounding and pathogen infection. Linkage of extensins with LRR motifs is highly significant in defending host tissues against pathogen invasion. Overexpression of PGIPs or expression of several PGIPs in a plant tissue, and perhaps manipulation of extensin expression could be possible strategies for disease management. & 2004 Elsevier GmbH. All rights reserved.

Item Type: Article
Uncontrolled Keywords: Resistance; Defence; Leucine-rich repeat; Plant–pathogen interaction; PGIPs; Extensins 094
Subjects: Microbiology
Depositing User: Dr. Aparna Maitra Pati
Date Deposited: 29 Dec 2011 11:45
Last Modified: 29 Dec 2011 11:45

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