Sharma, N and Sharma, A and Kumar, R and Shard, A and Sinha, Arun K (2010) One-Pot Two-Step Oxidative Cleavage of 1,2-Arylalkenes to Aryl Ketones Instead of Arylaldehydes in an Aqueous Medium: A Complementary Approach to Ozonolysis. European Jpurnal of Organic Chemistry. pp. 6025-6032.

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A new approach has been developed for a one-pot and selective oxidative cleavage of aryl- and 1,2-diarylalkenes leading to one-carbon shorter aryl ketones; thereby, providing a complementary approach to classical ozonolysis. The methodology was applicable to diverse aromatic and polyaromaticarylalkenes bearing electron-donating or -withdrawing groups on the aromatic ring. The protocol also provided a useful one-pot oxidative cleavage–condensation sequence, which could potentially have important applications in natural product total synthesis.

Item Type: Article
Uncontrolled Keywords: Cleavage reactions / Alkenes / Oxidation / Ketones / Microwave chemistry
Subjects: Natural Product Chemistry
Depositing User: Dr. Aparna Maitra Pati
Date Deposited: 02 Jan 2012 09:49
Last Modified: 02 Jan 2012 09:49

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