Swaroop, A and Sinha, Arun K and Chawla, R and Arora, R and Sharma, R K and Kumar, J K (2005) Isolation and Characterization of 1,3-Dicapryloyl-2-linoleoylglycerol:A Novel Triglyceride from Berries of Hippophae rhamnoides. Chemical and Pharmaceutical Bulletin, 53 (8). pp. 1021-1024. ISSN 0009-2363

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1,3-Dicapryloyl-2-linoleoylglycerol (1), a novel triglyceride, was isolated from berries of Hippophae rhamnoides. The structure was elucidated on the basis of MS, 1D and 2D NMR experiments including HMQC and HMBC. The metal chelating, free radical scavenging, and lipid peroxidation inhibiting properties of the compound were also estimated with particular reference to radiation protection. In case of metal chelation and superoxide ion scavenging, 1 showed maximum inhibition at 50m g/ml (11%) and 100m g/ml (55%), respectively, whereas in lipid peroxidation, 1 showed maximum inhibition (57%) at 2 mg/ml as compared to quercetin as a control.

Item Type: Article
Uncontrolled Keywords: Hippophae rhamnoides; Elaeagnaceae; 1,3-dicapryloyl-2-linoleoylglycerol; metal chelation; free radical scavenging; lipid peroxidation
Subjects: Chemical Engineering
Depositing User: Dr. Aparna Maitra Pati
Date Deposited: 27 Dec 2011 11:31
Last Modified: 06 Feb 2012 07:18
URI: http://ihbt.csircentral.net/id/eprint/180

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