Sharma , U K and Sharma, Nandini and Kumar, Rajesh and Sinha, Arun K (2013) Biocatalysts for multicomponent Biginelli reaction: bovine serum albumin triggered waste-free synthesis of 3,4-dihydropyrimidin-2-(1H)-ones. Journal of Amino Acids, 44. pp. 1031-1037.

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Bovine serum albumin (BSA) promoted simple and efficient one-pot procedure was developed for the direct synthesis of 3,4-dihydropyrimidin-2(1H)-ones including potent mitotic kinesin Eg5 inhibitor monastrol under mild reaction conditions. The catalyst recyclability and gram scale synthesis have also been demonstrated to enhance the practical utility of process.

Item Type: Article
Uncontrolled Keywords: Biginelli condensation; Bovine Serum Albumin; Biocatalysis; Sustainable Chemistry
Subjects: Natural Product Chemistry
Depositing User: Dr. Aparna Maitra Pati
Date Deposited: 03 Apr 2013 11:08
Last Modified: 03 Apr 2013 11:08

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