Shah, Wajaht A and Dar, Mohd Yousuf and Zagar, M. Iqbal and Agnihotri, Vijai K and Qurishi, M.A and Singh , Bikram (2012) Chemical composition and antimicrobial activity of the leaf essential oil of Skimmia laureola growing wild in Jammu and Kashmir, India. Natural Product Research. pp. 1-5.

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Abstract

The analysis of Skimmia laureola hydrodistillate by gas chromatography coupled with mass spectrometry revealed the presence of 20 constituents, representing 94.6% of the total oil. The major constituents of oil were linalyl acetate (33.0%), linalool (25.0%), limonene (8.1%), α-terpineol (5.9%) and geranyl acetate (5.9%). The monoterpene (93.4%) rich essential oil was evaluated for its antibacterial and antifungal activities against seven microorganisms by agar diffusion and microdilution methods. The oil showed appreciable antimicrobial effects against all Gram-positive bacteria tested, including methicillin-resistant Staphylococcus aureus and Staphylococcus epidermidis with MIC values 32 and 64 mgmL-1, respectively. The oil also exhibited strong fungicidal activity against Aspergillus niger and Penicillium chrysogenum with MIC value in the range 32–16 mgmL-1. The oil could be used in the formulation of antimicrobial agents.

Item Type:	Article
Uncontrolled Keywords:	essential oil; oxygenated monoterpenes; linalyl acetate; MIC; MBC; antibacterial; antifungal activity
Subjects:	Natural Product Chemistry
Divisions:	UNSPECIFIED
Depositing User:	Dr. Aparna Maitra Pati
Date Deposited:	03 Jan 2013 10:38
Last Modified:	03 Jan 2013 10:38
URI:	http://ihbt.csircentral.net/id/eprint/1240

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