Chaudhary, A and Das, Pralay and Mishra, Awanish and Kaur, Pushpinder and Singh , Bikram and Goel, R K (2012) Naturally occurring himachalenes to benzocycloheptene amino vinyl bromide derivatives: as antidepressant molecules. Molecular Diversity, 16. pp. 357-366.

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A new series of benzocycloheptene amino vinyl bromide derivatives (9a–9m) were synthesized from isomeric mixture of himachalenes through two-step synthesis. The unusual structure of benzocycloheptene amino vinyl bromide derivative (9a) was confirmed by NMRand X-ray crystallography analyses. The newly synthesized amino vinyl bromide derivatives of benzocycloheptene were further evaluated for their antidepressant activities. The compound 9c had shown significant reduction in the immobility period.

Item Type: Article
Uncontrolled Keywords: Vinyl halide · Benzocycloheptene amino vinyl bromide derivatives · Antidepressant · Himachalene
Subjects: Natural Product Chemistry
Depositing User: Dr. Aparna Maitra Pati
Date Deposited: 03 Jan 2013 10:50
Last Modified: 03 Jan 2013 10:50

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