csir, ihbt (2009) A PROCESS FOR OBTAINING b-AESCIN FROM INDIAN HORSE CHESTNUT (AESCULUS INDICA). 274/DEL/2003 (231553).

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Abstract

A process for obtaining p-aescin from Indian horse chestnut (Aesculus indica The present invention relates to development of a process for purification of (3-aescin from Indian horse chestnut (Aesculus indica). Aescin was obtained from Indian horse chestnut (Aesculus indica seeds) by drying, grinding and extracting with water and ethyl/methyl alcohol mixture followed by removal of organic solvent and fractionation of aqueous layer with butanol/ isopropanol saturated with water. Treating the organic layer i.e. Butanol/isopropanol fraction with base in a separating funnel with gentle shaking. Washing of base treated organic layer with water saturated with butanol followed by passing of organic layer through acidic alumina. Distilling the organic layer to yield aescin as white amorphous powder. The yield is 2.0-3.0% and purity is minimum 90%.

Item Type:	Patent
Subjects:	Natural Product Chemistry
Divisions:	UNSPECIFIED
Depositing User:	Dr. Aparna Maitra Pati
Date Deposited:	07 Jan 2013 11:29
Last Modified:	07 Jan 2013 11:29
URI:	http://ihbt.csircentral.net/id/eprint/1032

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